Imisopasem manganese

CAS No. 218791-21-0

Imisopasem manganese ( M-40403;GC-4419 )

Catalog No. M13490 CAS No. 218791-21-0

A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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100MG 896 Get Quote
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Biological Information

  • Product Name
    Imisopasem manganese
  • Note
    Research use only, not for human use.
  • Brief Description
    A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.
  • Description
    A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen; significantly mitigates the increased sensitivity of old fibroblasts to ionizing radiation and chemotherapy and partially restores mitochondrial function without affecting ionizing radiation or chemotherapy-induced cancer cell killing.Chemotherapeutic Agents Phase 2 Clinical
  • Synonyms
    M-40403;GC-4419
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Cancer
  • Indication
    Chemotherapeutic

Chemical Information

  • CAS Number
    218791-21-0
  • Formula Weight
    479.35
  • Molecular Formula
    C21H31Cl2MnN5
  • Purity
    >98% (HPLC)
  • Solubility
    H2O: 16 mg/mL (Need ultrasonic and warming)
  • SMILES
    [H][N@]1([C@H]2[C@H]3CCCC2)CC4=[N]5C(C[N]6([H])[C@H]7CCCC[C@H]7[N@@]([Mn]861(Cl)5Cl)([H])CC[N@@]38[H])=CC=C4
  • Chemical Name
    Manganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7H-dibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]-, (PB-7-11-2344'3')-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tuder RM, et al. Am J Respir Cell Mol Biol. 2003 Jul;29(1):88-97.
2. Mapuskar KA, et al. Cancer Res. 2017 Aug 1. pii: canres.0106.2017.
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