Imisopasem manganese
CAS No. 218791-21-0
Imisopasem manganese ( M-40403;GC-4419 )
Catalog No. M13490 CAS No. 218791-21-0
A small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
50MG | 730 | Get Quote |
|
100MG | 896 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameImisopasem manganese
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NoteResearch use only, not for human use.
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Brief DescriptionA small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen.
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DescriptionA small-molecule superoxide dismutase (SOD) mimetic that converts superoxide to hydrogen peroxide and molecular oxygen; significantly mitigates the increased sensitivity of old fibroblasts to ionizing radiation and chemotherapy and partially restores mitochondrial function without affecting ionizing radiation or chemotherapy-induced cancer cell killing.Chemotherapeutic Agents Phase 2 Clinical
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SynonymsM-40403;GC-4419
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCancer
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IndicationChemotherapeutic
Chemical Information
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CAS Number218791-21-0
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Formula Weight479.35
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Molecular FormulaC21H31Cl2MnN5
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Purity>98% (HPLC)
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SolubilityH2O: 16 mg/mL (Need ultrasonic and warming)
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SMILES[H][N@]1([C@H]2[C@H]3CCCC2)CC4=[N]5C(C[N]6([H])[C@H]7CCCC[C@H]7[N@@]([Mn]861(Cl)5Cl)([H])CC[N@@]38[H])=CC=C4
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Chemical NameManganese, dichloro[(4aR,13aR,17aR,21aR)-1,2,3,4,4a,5,6,12,13,13a,14,15,16,17,17a,18,19,20,21,21a-eicosahydro-11,7-nitrilo-7H-dibenzo[b,h][1,4,7,10]tetraazacycloheptadecine-κN5,κN13,κN18,κN21,κN22]-, (PB-7-11-2344'3')-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tuder RM, et al. Am J Respir Cell Mol Biol. 2003 Jul;29(1):88-97.
2. Mapuskar KA, et al. Cancer Res. 2017 Aug 1. pii: canres.0106.2017.
2. Mapuskar KA, et al. Cancer Res. 2017 Aug 1. pii: canres.0106.2017.
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